Blackmores is renowned for offering a highly-pure, highly bio-available product that helps to ensure effectiveness and viability once in your system. They employ highly-specialized quality assurance teams that perform rigorous testing through the use of sophisticated analysis technologies.

2. Swisse

Swisse supplements are ultra-pure, hypoallergenic, and independently tested for potency. These supplements live up to their name by providing one of the purest and uniquely-blended products on the market. They are among the elite tier of supplements brands that frequently sell directly to Health Practitioners.

3. Ocean Health

Ocean health is another manufacturer that touts the classification of being doctor-approved, and is quite frequently prescribed by Health Practitioners and integrative doctors. They are the most-trusted supplement manufacturers in Singapore. As with many manufacturers on this list, Ocean Health has been able to develop quality products and unique synergistic blends by relying on science-based research conducted by their own investigations.

4. Thorne Research

Thorne Research is one of the industries leading manufacturers of pharmaceutical grade supplements, with an extensive product line and a quality line of specially-formulated products that aren’t found anywhere else. They are a NSF cGMP facility, and maintain some of the most rigid quality assurance practices within the country. Thorne Research has also partnered with such health authorities as The Mayo Clinic to develop clinical trials meant to help provide useful data on the effectiveness of supplements in addressing modern health concerns. As opposed to many supplement manufacturers, Thorne Research doesn’t simply abide by FDA regulations; they help define them, and push to increase their stringency on a regular basis.

5. Douglas Laboratories

Douglas Laboratories has been around for over 60 years, hailing as one of the most well-respected manufacturers of pharmaceutical grade supplements on the market. They offer a wide variety of supplements and are most-renowned for addressing metabolic issues through natural endocrine supporters as well as highly bioavailable enzyme formulas. Douglas Laboratories is a socially-responsible company which donates a portion of their revenue to SOS Children’s villages, which helps care for orphaned and abandoned children.

6. Metagenics
Metagenics was Founded in 1983, and this California based manufacturer prides themselves in their utilization of science-backed supplements. They have conducted extensive research in the field of nutrigenomics—using supplements to help establish and maintain balance on a genetic level. By using this unique and powerful approach, Metagenics have firmly carved out a position amid the top five list of best pharmaceutical grade supplement manufacturers. Metagenics boasts the following quality assurances:

7. Vital Nutrients

Vital Nutrients is another pharmaceutical grade supplement manufacturer that is trusted by doctors to treat a variety of health conditions. They have their own in-house team of qualified health professionals to develop their products in accordance with scientific data. Their manufacturing facilities are certified cGMP by the FDA. Before one of their products hits the shelves, it is tested for Microbiological contaminants, residual solvents, heavy metals, aflatoxins, pesticides, melamine, PCBs, Dixions, and GMOs

8. Klaire Labs

Klaire labs, owned by parent company ProThera, has a strong focus on digestive health, and offers a very powerful line of digestive and proteolytic enzymes which are hypo-allergenic and very pure. Klaire Labs’ Ther-Biotic Detoxification Support probiotic product is regarded by many as being un-comparably potent. It can be a bit pricey, has to ship 2 Day FedEx, and has to have a special ice-pack packing supplied. Klaire Labs produces the most-potent products available for commercial sale, and is trusted by healthcare professionals worldwide to deliver powerful results.

The supplement brands on this list represent some of the most-powerful compounds on the market